A variety of circumstantial evidence from humans has implicated the B cell antigen receptor (BCR) in the genesis of B cell lymphomas.We generated mouse models designed to test this possibility directly, and we found that both the constitutive and antigen-stimulated state of a clonal BCR affected the rate and outcome of lymphomagenesis initiated by
In recent decades the Southeast Asia Countries have been affected by haze pollution which is caused by human activities in burning land/forest for plantation and/or agriculture.Indonesia is one of the major sources of the haze pollution in the region.The pollution does not stop at national borders only, but also causing transboundary pollution to t
Gastrointestinal cancers (GICs) remain the most diagnosed cancers and Sticker Packs accounted for the highest cancer-related death globally.The prognosis and treatment outcomes of many GICs are poor because most of the cases are diagnosed in advanced metastatic stages.This is primarily attributed to the deficiency of effective and reliable early di